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Evolving Diagnostic Approach of Pulmonary Salivary Gland-type Tumors.

Authors :
Sood R
Jain D
Source :
Surgical pathology clinics [Surg Pathol Clin] 2024 Jun; Vol. 17 (2), pp. 227-241. Date of Electronic Publication: 2023 Dec 26.
Publication Year :
2024

Abstract

Pulmonary salivary gland-type, although bear resemblance to their salivary gland counterparts, present a diagnostic challenge due to their rarity. Clinical features overlap with lung carcinoma; however, management strategies and outcomes are distinct. Onus falls on the pathologist to avoid misinterpretation of small biopsies especially in young, nonsmokers with slow growing or circumscribed endobronchial growths. A combination of cytokeratin, myoepithelial immunohistochemical markers, and identification of signature molecular alteration is invaluable in differentiation from lung cancers and subtyping the pulmonary salivary gland-type tumor.<br />Competing Interests: Disclosure Authors have no commercial or financial conflicts of interest.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1875-9157
Volume :
17
Issue :
2
Database :
MEDLINE
Journal :
Surgical pathology clinics
Publication Type :
Academic Journal
Accession number :
38692807
Full Text :
https://doi.org/10.1016/j.path.2023.11.001