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Evolving Diagnostic Approach of Pulmonary Salivary Gland-type Tumors.
- Source :
-
Surgical pathology clinics [Surg Pathol Clin] 2024 Jun; Vol. 17 (2), pp. 227-241. Date of Electronic Publication: 2023 Dec 26. - Publication Year :
- 2024
-
Abstract
- Pulmonary salivary gland-type, although bear resemblance to their salivary gland counterparts, present a diagnostic challenge due to their rarity. Clinical features overlap with lung carcinoma; however, management strategies and outcomes are distinct. Onus falls on the pathologist to avoid misinterpretation of small biopsies especially in young, nonsmokers with slow growing or circumscribed endobronchial growths. A combination of cytokeratin, myoepithelial immunohistochemical markers, and identification of signature molecular alteration is invaluable in differentiation from lung cancers and subtyping the pulmonary salivary gland-type tumor.<br />Competing Interests: Disclosure Authors have no commercial or financial conflicts of interest.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1875-9157
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Surgical pathology clinics
- Publication Type :
- Academic Journal
- Accession number :
- 38692807
- Full Text :
- https://doi.org/10.1016/j.path.2023.11.001