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[Recurrent herpetic erosion of the cornea: diagnosis, treatment and prevention of recurrences].
- Source :
-
Vestnik oftalmologii [Vestn Oftalmol] 2024; Vol. 140 (2. Vyp. 2), pp. 102-108. - Publication Year :
- 2024
-
Abstract
- A group of patients was found to have a special form of recurrent corneal erosion caused by types I and II herpes virus. This form represents an independent form of ophthalmic herpes - herpetic recurrent erosion (HRE) of the cornea. The herpetic etiology of recurrent corneal erosion was confirmed by the immunofluorescence study of scraping from the conjunctiva, which revealed a high concentration of the herpes simplex virus antigen. Treatment of patients (171 patients, 182 eyes) with HRE included 2 consecutive stages: stage I - relief of acute symptoms of the disease with the help of conservative treatment (instillations of interferon inducers, autologous serum, corneal protectors, tear substitutes, use of therapeutic soft contact lenses); in some cases, phototherapeutic keratectomy was used in the absence of the effect of conservative therapy, as well as in the localization of the focus in the optical zone. Stage II involved anti-relapse therapy based on the use of a Russian-produced herpes vaccine in the intercurrent period. After vaccination, observation for 2 years or more showed that 81.3% of patients achieved clinical recovery (complete cessation of HRE recurrences), 15.8% had a decrease in the frequency and severity of relapses, while 2.9% of patients did not respond to the treatment.
- Subjects :
- Humans
Male
Female
Middle Aged
Adult
Recurrence
Cornea
Treatment Outcome
Antiviral Agents therapeutic use
Secondary Prevention methods
Eye Infections, Viral diagnosis
Eye Infections, Viral etiology
Eye Infections, Viral prevention & control
Eye Infections, Viral therapy
Keratitis, Herpetic diagnosis
Keratitis, Herpetic etiology
Keratitis, Herpetic therapy
Keratitis, Herpetic prevention & control
Subjects
Details
- Language :
- Russian
- ISSN :
- 0042-465X
- Volume :
- 140
- Issue :
- 2. Vyp. 2
- Database :
- MEDLINE
- Journal :
- Vestnik oftalmologii
- Publication Type :
- Academic Journal
- Accession number :
- 38739138
- Full Text :
- https://doi.org/10.17116/oftalma2024140022102