Diffuse Intense 18 F-PSMA-1007 Uptake of the Breasts in a Woman With TFE3-Rearranged Renal Cell Carcinoma.

Abstract: A 23-year-old woman presenting with gross hematuria was found to have a left renal mass suspicious for renal cell carcinoma on abdominal contrast-enhanced CT. An 18 F-PSMA-1007 PET/CT scan was performed for evaluating the renal mass. 18 F-PSMA-1007 PET/CT showed focal activity of the renal mass, which was a transcription factor E3-rearranged renal cell carcinoma proved after nephrectomy. Surprisingly, diffuse heterogeneous intense activity of the bilateral breasts and moderate activity of the right accessory breast was observed. There was no morphological abnormality of the bilateral breasts and right accessory breast on CT images, indicating physiological PSMA uptake.
Competing Interests: Conflicts of interest and sources of funding: This work was supported by the “Discipline Climbing 234 Plan For Disciplinary Platform Construction” of The First Affiliated Hospital of Naval Medical University (no. 2020YPT002) and The First Affiliated Hospital of Naval Medical University “Guhai Plan in the 14th Five-Year Plan Period” (grant no. GH145-22 and GH145XKQ-03).
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