Back to Search
Start Over
A high-resolution phase-contrast microscopy system for label-free imaging in living cells.
- Source :
-
Cell structure and function [Cell Struct Funct] 2024 Jun 22; Vol. 49 (1), pp. 21-29. Date of Electronic Publication: 2024 May 29. - Publication Year :
- 2024
-
Abstract
- Cell biologists have long sought the ability to observe intracellular structures in living cells without labels. This study presents procedures to adjust a commercially available apodized phase-contrast (APC) microscopy system for better visualizing the dynamic behaviors of various subcellular organelles in living cells. By harnessing the versatility of this technique to capture sequential images, we could observe morphological changes in cellular geometry after virus infection in real time without probes or invasive staining. The tune-up APC microscopy system is a highly efficient platform for simultaneously observing the dynamic behaviors of diverse subcellular structures with exceptional resolution.
Details
- Language :
- English
- ISSN :
- 1347-3700
- Volume :
- 49
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cell structure and function
- Publication Type :
- Academic Journal
- Accession number :
- 38797697
- Full Text :
- https://doi.org/10.1247/csf.24018