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Epimedium Linn: A Comprehensive Review of Phytochemistry, Pharmacology, Clinical Applications and Quality Control.

Authors :
Chen XL
Li SX
Ge T
Zhang DD
Wang HF
Wang W
Li YZ
Song XM
Source :
Chemistry & biodiversity [Chem Biodivers] 2024 Aug; Vol. 21 (8), pp. e202400846. Date of Electronic Publication: 2024 Jul 09.
Publication Year :
2024

Abstract

Epimedium genus is a traditional Chinese medicine, which has functions of tonifying kidney and yang, strengthening tendons and bones, dispelling wind and emoving dampness. It is mainly used for the treatment of impotence and spermatorrhea, osteoporosis, Parkinson's, Alzheimer's, and cardiovascular diseases. The aim of this review is to provide a systematic summary of the phytochemistry, pharmacology, and clinical applications of the Epimedium Linn. In this paper, the relevant literature on Epimedium Linn. was collected from 1987 to the present day, and more than 274 chemical constituents, including flavonoids, phenylpropanoids, lignans, phenanthrenes, and others, were isolated from this genus. Modern pharmacological studies have shown that Epimedium Linn. has osteoprotective, neuroprotective, cardiovascular protective, and immune enhancing pharmacological effects. In addition, Epimedium Linn. has been commonly used to treat osteoporosis, erectile dysfunction, hypertension and cardiovascular disease. In this paper, the distribution of resources, chemical compositions, pharmacological effects, clinical applications and quality control of Epimedium Linn. are progressed to provide a reference for further research and development of the resources of this genus.<br /> (© 2024 Wiley-VHCA AG, Zurich, Switzerland.)

Details

Language :
English
ISSN :
1612-1880
Volume :
21
Issue :
8
Database :
MEDLINE
Journal :
Chemistry & biodiversity
Publication Type :
Academic Journal
Accession number :
38801026
Full Text :
https://doi.org/10.1002/cbdv.202400846