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[Managing Superwarfarin Poisoning: A Challenging Case].

Authors :
Zavadzki G
Inzunza Robles J
San Martín MF
Gutiérrez Torres W
Ramos-Rojas JT
Gauna-Cordero J
Bigossi Aguiar N
Source :
Revista medica de Chile [Rev Med Chil] 2023 Jun; Vol. 151 (6), pp. 797-800.
Publication Year :
2023

Abstract

Human intoxication by long-acting anticoagulant rodenticides, known as superwarfarins, causes coagulopathy that is difficult to manage. We present the case of a 42-year-old man who ingested a toxic dose of rodenticide in a suicide attempt, evolving with epistaxis, INR of 11.6, and needing hospitalization. For seven days, serial controls of coagulation tests were carried out, with optimization of different doses of Vitamin K supplementation. The case highlights this type of anticoagulant's potency and prolonged half-life (approximately six weeks), which requires regular clinical control and satisfactory treatment adherence.

Details

Language :
Spanish; Castilian
ISSN :
0717-6163
Volume :
151
Issue :
6
Database :
MEDLINE
Journal :
Revista medica de Chile
Publication Type :
Academic Journal
Accession number :
38801389
Full Text :
https://doi.org/10.4067/s0034-98872023000600797