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Risk of central line-associated bloodstream infections during COVID-19 pandemic in intensive care patients in a tertiary care centre in Saudi Arabia.
- Source :
-
Epidemiology and infection [Epidemiol Infect] 2024 Jun 03; Vol. 152, pp. e95. Date of Electronic Publication: 2024 Jun 03. - Publication Year :
- 2024
-
Abstract
- This retrospective study compared central line-associated bloodstream infection (CLABSI) rates per 1 000 central line days, and overall mortality before and during the COVID-19 pandemic in adult, paediatric, and neonatal ICU patients at King Abdul-Aziz Medical City-Riyadh who had a central line and were diagnosed with CLABSI according to the National Healthcare Safety Network standard definition. The study spanned between January 2018 and December 2019 (pre-pandemic), and January 2020 and December 2021 (pandemic). SARS-CoV-2 was confirmed by positive RT-PCR testing. The study included 156 CLABSI events and 46 406 central line days; 52 and 22 447 (respectively) in pre-pandemic, and 104 and 23 959 (respectively) during the pandemic. CLABSI rates increased by 2.02 per 1 000 central line days during the pandemic period (from 2.32 to 4.34, p  < 0.001). Likewise, overall mortality rates increased by 0.86 per 1 000 patient days (from 0.93 to 1.79, p  = 0.003). Both CLABSI rates (6.18 vs. 3.7, p  = 0.006) and overall mortality (2.72 vs. 1.47, p  = 0.014) were higher among COVID-19 patients compared to non-COVID-19 patients. The pandemic was associated with a substantial increase in CLABSI-associated morbidity and mortality.
- Subjects :
- Humans
Saudi Arabia epidemiology
Retrospective Studies
Male
Female
Middle Aged
Adult
Aged
Intensive Care Units statistics & numerical data
SARS-CoV-2
Child
Infant, Newborn
Infant
Adolescent
Child, Preschool
Young Adult
COVID-19 epidemiology
COVID-19 mortality
Tertiary Care Centers statistics & numerical data
Catheter-Related Infections epidemiology
Catheter-Related Infections mortality
Catheterization, Central Venous adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1469-4409
- Volume :
- 152
- Database :
- MEDLINE
- Journal :
- Epidemiology and infection
- Publication Type :
- Academic Journal
- Accession number :
- 38825764
- Full Text :
- https://doi.org/10.1017/S0950268824000736