Back to Search
Start Over
Neonatal and Maternal Ichthyosiform Dermopathy in Association with Kava Use during Pregnancy.
- Source :
-
Journal of medical toxicology : official journal of the American College of Medical Toxicology [J Med Toxicol] 2024 Jul 11; Vol. 20 (3), pp. 308-313. Date of Electronic Publication: 2024 Jun 05. - Publication Year :
- 2024
-
Abstract
- Introduction: Kava, a substance derived from the Piper methysticum plant, is enjoying a surge in popularity in the United States due to its purported anxiolytic and analgesic effects. Though ichthyosiform dermopathy is a known adverse effect associated with chronic kava exposure in adults, dermopathy in a newborn due to maternal kava use has not yet been described.<br />Case Report: This is a case of a 41-year-old woman who was taking a combination kava/kratom product throughout her pregnancy. She developed an ichthyosiform dermopathy that resolved after she stopped using the product postpartum. Her male infant had a neonatal course complicated by both neonatal opioid withdrawal syndrome, attributed to maternal kratom and buprenorphine use, as well as a diffuse ichthyosiform rash similar to descriptions of kava ichthyosiform dermopathy in adults. His neonatal course was complicated by Group B streptococcus and Serratia marscecens bacteremia (treated with antibiotics) and seizures (treated with lorazepam and phenobarbital). His rash resolved completely by day of life 22. At 9-month outpatient follow-up, he had no dermatologic abnormalities or rash recurrence.<br />Discussion: Maternal kava use during pregnancy may cause fetal dermopathy presenting as an acquired ichthyosis. More public education is needed about the potential consequences of kava use, particularly during pregnancy.<br /> (© 2024. American College of Medical Toxicology.)
Details
- Language :
- English
- ISSN :
- 1937-6995
- Volume :
- 20
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of medical toxicology : official journal of the American College of Medical Toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 38839731
- Full Text :
- https://doi.org/10.1007/s13181-024-01016-x