Minimally Invasive Blood Collection for an Mpox Serosurvey among People Experiencing Homelessness.

Background: People experiencing homelessness (PEH) are underrepresented in public health and clinical research. Study methods that can improve participation by this group are needed.
Methods: In late 2022, the Centers for Disease Control and Prevention conducted an mpox serological survey using venipuncture among PEH in San Francisco, California. Blood collection by a minimally invasive device was offered if venipuncture was not possible or preferred. Participants who had a successful blood draw using the device were asked about device acceptability.
Results: Of the 209 successful blood collections, 137 (66%) were among participants who underwent venipuncture and 72 (34%) were among participants who used the device. Use of the device increased overall blood collection participation by 53%. Participants reported high acceptability and preference for the device over venipuncture.
Conclusions: Minimally invasive blood collection devices may increase participation and representation of PEH in serosurveys.
(Published by Oxford University Press on behalf of Association for Diagnostics & Laboratory Medicine 2024.)