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Contemporary radiation therapy use in Hodgkin lymphoma.

Authors :
Saifi O
Hoppe BS
Source :
Seminars in hematology [Semin Hematol] 2024 Aug; Vol. 61 (4), pp. 263-269. Date of Electronic Publication: 2024 May 31.
Publication Year :
2024

Abstract

Radiation therapy assumes a pivotal role in Hodgkin lymphoma management, especially within combined modality therapy. It serves as a cornerstone in early-stage disease and in mitigating high-risk instances of local relapse in advanced stages. Over recent decades, radiation therapy has undergone significant advancements, notably alongside diagnostic imaging improvements, facilitating the reduction of radiation field size and dosage. This progress has notably led to minimized toxicity while upholding treatment efficacy. This comprehensive review extensively evaluates the indications and advancements in radiation therapy for Hodgkin lymphoma, with a primary focus on enhancing treatment efficacy while minimizing radiation-related toxicities. The exploration encompasses a detailed examination of various radiation fields, techniques and delivery modalities employed in Hodgkin lymphoma treatment, including intensity-modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT), and proton therapy. It delves into the intricacies of optimal dose selection and treatment planning strategies aimed at achieving maximal disease control while concurrently minimizing the risk of long-term side effects.<br />Competing Interests: Declaration of competing interest None of the authors have relevant conflict of interest related to this work.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1532-8686
Volume :
61
Issue :
4
Database :
MEDLINE
Journal :
Seminars in hematology
Publication Type :
Academic Journal
Accession number :
38897840
Full Text :
https://doi.org/10.1053/j.seminhematol.2024.05.006