Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease.

Authors :: Stefansson H
Walters GB
Sveinbjornsson G
Tragante V
Einarsson G
Helgason H
Sigurðsson A
Beyter D
Snaebjarnarson AS
Ivarsdottir EV
Thorleifsson G
Halldorsson BV
Norddahl G
Styrkarsdottir U
Sturluson A
Holm H
Helgason A
Moore K
Eggertsson HP
Oddsson AH
Jonsdottir GA
Gunnarsson AF
Bjornsdottir G
Gisladottir RS
Thorgeirsson TE
Skuladottir A
Gudbjartsson DF
Sulem P
Jonsson P
Thordardottir S
Snaedal J
Eyjolfsdottir H
Creese B
Ballard C
Corbett A
Vasconcelos Da Silva M
Aarsland D
Andreassen OA
Selbæk G
Djurovic S
Stordal E
Fladby T
Haavik J
Igland J
Giil LM
Eriksson S
Hallmans G
Lövheim H
Lopatko Lindman K
Trupp M
Forsgren L
Werge T
Banasik K
Brunak S
Ullum H
Frikke-Schmidt R
Ostrowski SR
Didriksen M
Sørensen E
Simonsen AH
Nielsen JE
Waldemar G
Pedersen OB
Erikstrup C
Knowlton KU
Nadauld LD
Stefansson K
Source :: The New England journal of medicine [N Engl J Med] 2024 Jun 20; Vol. 390 (23), pp. 2217-2219.
Publication Year :: 2024

Subjects :: Aged
Female
Humans
Male
Apolipoproteins E metabolism
Cholesterol, LDL metabolism
Clusterin metabolism
Genetic Predisposition to Disease genetics
Homozygote
Mutation, Missense
Alzheimer Disease ethnology
Alzheimer Disease genetics
Alzheimer Disease metabolism
Membrane Glycoproteins genetics
Membrane Glycoproteins metabolism
Receptors, Immunologic genetics
Receptors, Immunologic metabolism

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