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Synthesis and Biological Evaluation of Benzamide Compounds as Insecticides Agents Against Spodoptera Frugiperda (Lepidoptera: Noctuidae).

Authors :
Abd El-Lateef HM
Khalaf MM
Gouda M
Abdelhamid AA
Gad MA
Source :
Chemistry & biodiversity [Chem Biodivers] 2024 Aug; Vol. 21 (8), pp. e202400948. Date of Electronic Publication: 2024 Aug 02.
Publication Year :
2024

Abstract

Due to its severe damage, Spodoptera frugiperda is receiving attention as one of the biggest dangers to world food security. Although there are numerous insecticides that are widely and successfully used to control S. frugiperda, they do not have an immediate effect. In our work focusing for synthesized twelve novel benzamide derivatives and examined their insecticidal effectiveness against S. frugiperda larvae in their second & fourth larvae instars, with the aim of further improving the insecticidal activity based on combination principles. Several spectroscopic methods, including elemental analysis, NMR & infrared spectroscopy, were employed for confirming the structure of the newly designed products. It has been discovered that most compounds show good of promising efficacy. With an LC <subscript>50</subscript> of 24.8 mg/L for larvae in the second instar & 56.2 mg/L for larvae in the fourth instar, compound 23 was the most active. Among all compounds 11, 22 and 20 exhibited excellent results. Furthermore, a number of biological and histopathological properties of the demonstration compounds of the produced goods under laboratory conditions were also examined. This work further demonstrates the anti-proliferation of S. frugiperda and offers fresh ideas for the manufacture of benzamide derivatives.<br /> (© 2024 Wiley-VHCA AG, Zurich, Switzerland.)

Details

Language :
English
ISSN :
1612-1880
Volume :
21
Issue :
8
Database :
MEDLINE
Journal :
Chemistry & biodiversity
Publication Type :
Academic Journal
Accession number :
38899798
Full Text :
https://doi.org/10.1002/cbdv.202400948