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The impact of previous SARS-CoV-2 infection on post-vaccine adverse events in individuals vaccinated with TURKOVAC or CoronaVac -inactivated COVID-19 vaccines.
- Source :
-
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2024 Dec 31; Vol. 20 (1), pp. 2346388. Date of Electronic Publication: 2024 Jun 26. - Publication Year :
- 2024
-
Abstract
- This study- a secondary analysis of data from a randomized, observer-blinded, non-inferiority study among volunteers between 18-55 y old in Türkiye- evaluated the impact of previous SARS-CoV-2 infection before the first dose of inactive TURKOVAC on post-vaccine local and systemic adverse events (AEs) comparing with CoronaVac. Of 1266 participants analyzed, 27.7% had a previous COVID-19 history. Local and systemic AEs were observed in 37.3% and 39% of the participants. The frequency of AEs was slightly higher in the first 30 minutes and 24 hours among participants with a COVID-19 history; none were severe. 1203 participants had a second dose vaccination, and 27.3% had a history of COVID-19. The frequencies of local and systemic AEs after the second dose were similar between those with and without a COVID-19 history. The TURKOVAC and CoronaVac showed similar frequencies of local and systemic AEs in the first 30 minutes after vaccination.
- Subjects :
- Humans
Adult
Male
Middle Aged
Female
Young Adult
Adolescent
SARS-CoV-2 immunology
Vaccination adverse effects
COVID-19 prevention & control
COVID-19 Vaccines adverse effects
COVID-19 Vaccines administration & dosage
Vaccines, Inactivated adverse effects
Vaccines, Inactivated administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 2164-554X
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Human vaccines & immunotherapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 38924774
- Full Text :
- https://doi.org/10.1080/21645515.2024.2346388