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Assessment of Survival Kinetics for Emergent Highly Pathogenic Clade 2.3.4.4 H5Nx Avian Influenza Viruses.
- Source :
-
Viruses [Viruses] 2024 May 31; Vol. 16 (6). Date of Electronic Publication: 2024 May 31. - Publication Year :
- 2024
-
Abstract
- High pathogenicity avian influenza viruses (HPAIVs) cause high morbidity and mortality in poultry species. HPAIV prevalence means high numbers of infected wild birds could lead to spill over events for farmed poultry. How these pathogens survive in the environment is important for disease maintenance and potential dissemination. We evaluated the temperature-associated survival kinetics for five clade 2.3.4.4 H5Nx HPAIVs (UK field strains between 2014 and 2021) incubated at up to three temperatures for up to ten weeks. The selected temperatures represented northern European winter (4 °C) and summer (20 °C); and a southern European summer temperature (30 °C). For each clade 2.3.4.4 HPAIV, the time in days to reduce the viral infectivity by 90% at temperature T was established (D <subscript>T</subscript> ), showing that a lower incubation temperature prolonged virus survival (stability), where D <subscript>T</subscript> ranged from days to weeks. The fastest loss of viral infectivity was observed at 30 °C. Extrapolation of the graphical D <subscript>T</subscript> plots to the x-axis intercept provided the corresponding time to extinction for viral decay. Statistical tests of the difference between the D <subscript>T</subscript> values and extinction times of each clade 2.3.4.4 strain at each temperature indicated that the majority displayed different survival kinetics from the other strains at 4 °C and 20 °C.
- Subjects :
- Animals
Kinetics
Poultry virology
Animals, Wild virology
Birds virology
Poultry Diseases virology
Poultry Diseases mortality
Influenza in Birds virology
Influenza in Birds mortality
Temperature
Influenza A virus pathogenicity
Influenza A virus genetics
Influenza A virus classification
Influenza A virus physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1999-4915
- Volume :
- 16
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Viruses
- Publication Type :
- Academic Journal
- Accession number :
- 38932181
- Full Text :
- https://doi.org/10.3390/v16060889