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Influence of reduced-port laparoscopic surgery on perioperative indicators, postoperative recovery, and serum inflammation in patients with colorectal carcinoma.
- Source :
-
World journal of gastrointestinal surgery [World J Gastrointest Surg] 2024 Jun 27; Vol. 16 (6), pp. 1734-1741. - Publication Year :
- 2024
-
Abstract
- Background: Conventional five-port laparoscopic surgery, the current standard treatment for colorectal carcinoma (CRC), has many disadvantages.<br />Aim: To assess the influence of reduced-port laparoscopic surgery (RPLS) on perioperative indicators, postoperative recovery, and serum inflammation indexes in patients with CRC.<br />Methods: The study included 115 patients with CRC admitted between December 2019 and May 2023, 52 of whom underwent conventional five-port laparoscopic surgery (control group) and 63 of whom underwent RPLS (research group). Comparative analyses were performed on the following dimensions: Perioperative indicators [operation time (OT), incision length, intraoperative blood loss (IBL), and rate of conversion to laparotomy], postoperative recovery (first postoperative exhaust, bowel movement and oral food intake, and bowel sound recovery time), serum inflammation indexes [high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6)], postoperative complications (anastomotic leakage, incisional infection, bleeding, ileus), and therapeutic efficacy.<br />Results: The two groups had comparable OTs and IBL volumes. However, the research group had a smaller incision length; lower rates of conversion to laparotomy and postoperative total complication; and shorter time of first postoperative exhaust, bowel movement, oral food intake, and bowel sound recovery; all of which were significant. Furthermore, hs-CRP, IL-6, and TNF-α levels in the research group were significantly lower than the baseline and those of the control group, and the total effective rate was higher.<br />Conclusion: RPLS exhibited significant therapeutic efficacy in CRC, resulting in a shorter incision length and a lower conversion rate to laparotomy, while also promoting postoperative recovery, effectively inhibiting the inflammatory response, and reducing the risk of postoperative complications.<br />Competing Interests: Conflict-of-interest statement: Dr. Cao has nothing to disclose.<br /> (©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1948-9366
- Volume :
- 16
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- World journal of gastrointestinal surgery
- Publication Type :
- Academic Journal
- Accession number :
- 38983325
- Full Text :
- https://doi.org/10.4240/wjgs.v16.i6.1734