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Effects of home-based EEG neurofeedback training as a non-pharmacological intervention for Parkinson's disease.
- Source :
-
Neurophysiologie clinique = Clinical neurophysiology [Neurophysiol Clin] 2024 Sep; Vol. 54 (5), pp. 102997. Date of Electronic Publication: 2024 Jul 10. - Publication Year :
- 2024
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Abstract
- Objectives: Aberrant movement-related cortical activity has been linked to impaired motor function in Parkinson's disease (PD). Dopaminergic drug treatment can restore these, but dosages and long-term treatment are limited by adverse side-effects. Effective non-pharmacological treatments could help reduce reliance on drugs. This experiment reports the first study of home-based electroencephalographic (EEG) neurofeedback training as a non-pharmacological candidate treatment for PD. Our primary aim was to test the feasibility of our EEG neurofeedback intervention in a home setting.<br />Methods: Sixteen people with PD received six home visits comprising symptomology self-reports, a standardised motor assessment, and a precision handgrip force production task while EEG was recorded (visits 1, 2 and 6); and 3 × 1-hr EEG neurofeedback training sessions to supress the EEG mu rhythm before initiating handgrip movements (visits 3 to 5).<br />Results: Participants successfully learned to self-regulate mu activity, and this appeared to expedite the initiation of precision movements (i.e., time to reach target handgrip force off-medication pre-intervention = 628 ms, off-medication post-intervention = 564 ms). There was no evidence of wider symptomology reduction (e.g., Movement Disorder Society Unified Parkinson's Disease Rating Scale Part III Motor Examination, off-medication pre-intervention = 29.00, off-medication post intervention = 30.07). Interviews indicated that the intervention was well-received.<br />Conclusion: Based on the significant effect of neurofeedback on movement-related cortical activity, positive qualitative reports from participants, and a suggestive benefit to movement initiation, we conclude that home-based neurofeedback for people with PD is a feasible and promising non-pharmacological treatment that warrants further research.<br />Competing Interests: Declaration of competing interest The authors declare that they have no conflict of interest.<br /> (Copyright © 2024 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1769-7131
- Volume :
- 54
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Neurophysiologie clinique = Clinical neurophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 38991470
- Full Text :
- https://doi.org/10.1016/j.neucli.2024.102997