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Preferred diuretic therapy for primary hypertension: Chlorthalidone or hydrochlorothiazide?
- Source :
-
JAAPA : official journal of the American Academy of Physician Assistants [JAAPA] 2024 Aug 01; Vol. 37 (8), pp. 1-2. Date of Electronic Publication: 2024 Jul 25. - Publication Year :
- 2024
-
Abstract
- Abstract: Because of its greater reduction of major adverse cardiovascular events (MACE), chlorthalidone is recommended over hydrochlorothiazide as the preferred diuretic for patients with primary hypertension. However, hydrochlorothiazide is more commonly prescribed than chlorthalidone for this condition. This article reviews recent studies investigating the effectiveness of chlorthalidone and hydrochlorothiazide in reducing MACE, to help clinicians make an evidence-based informed decision on which diuretic to prescribe.<br /> (Copyright © 2024 American Academy of Physician Associates.)
- Subjects :
- Humans
Cardiovascular Diseases prevention & control
Cardiovascular Diseases drug therapy
Chlorthalidone administration & dosage
Chlorthalidone therapeutic use
Hydrochlorothiazide administration & dosage
Hydrochlorothiazide therapeutic use
Hypertension drug therapy
Diuretics administration & dosage
Diuretics therapeutic use
Antihypertensive Agents administration & dosage
Antihypertensive Agents therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1547-1896
- Volume :
- 37
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- JAAPA : official journal of the American Academy of Physician Assistants
- Publication Type :
- Academic Journal
- Accession number :
- 39051700
- Full Text :
- https://doi.org/10.1097/01.JAA.0000000000000057