Back to Search
Start Over
Mortality patterns in Dutch diabetes outpatients.
- Source :
-
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Oct; Vol. 26 (10), pp. 4213-4224. Date of Electronic Publication: 2024 Jul 29. - Publication Year :
- 2024
-
Abstract
- Aim: Diabetes mellitus is a major cause of death. Outpatients with diabetes have more complications than patients in general practice; mortality patterns have only been studied in the total diabetes population. This study aims to assess mortality, causes, and predictors in outpatients with diabetes.<br />Materials and Methods: A cohort study, included people with diabetes mellitus from the nationwide Dutch Paediatric and Adult Registry of Diabetes (DPARD) visiting diabetes outpatient clinics in 2016-2020. DPARD data were linked to Statistics Netherlands (CBS), comprising data on mortality, ethnicity and education. All-cause and cardiovascular mortality rates were estimated using Cox proportional hazard regression.<br />Results: During a median follow-up of 3.1 years among 12 992 people with diabetes, mortality rates per 10 000 person-years were 67.7 in adult type 1 diabetes and 324.2 in type 2 diabetes. The major cause of non-cardiovascular death was malignancy. During the pandemic years of influenza (2018) and COVID (2020), mortality rates peaked. Age, smoking and an estimated glomerular filtration rate of <60 ml/min were associated with all-cause mortality. In type 2 diabetes, additional factors were male sex, body mass index <20 kg/m <superscript>2</superscript> , diabetes duration <1 year and hypertension.<br />Conclusions: Mortality among Dutch outpatients with diabetes is high. Smoking and renal failure were associated with mortality in both types. Further focus on early detection and treatment of mortality-associated factors may improve clinical outcomes.<br /> (© 2024 John Wiley & Sons Ltd.)
- Subjects :
- Humans
Netherlands epidemiology
Male
Female
Middle Aged
Adult
Aged
Cohort Studies
Registries
Young Adult
Risk Factors
Cardiovascular Diseases mortality
Cardiovascular Diseases epidemiology
Adolescent
Smoking epidemiology
Smoking adverse effects
Diabetes Mellitus, Type 2 mortality
Diabetes Mellitus, Type 2 complications
Diabetes Mellitus, Type 2 epidemiology
Diabetes Mellitus, Type 1 mortality
Diabetes Mellitus, Type 1 complications
Diabetes Mellitus, Type 1 epidemiology
Outpatients statistics & numerical data
COVID-19 mortality
COVID-19 epidemiology
COVID-19 complications
Cause of Death
Subjects
Details
- Language :
- English
- ISSN :
- 1463-1326
- Volume :
- 26
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Diabetes, obesity & metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 39072872
- Full Text :
- https://doi.org/10.1111/dom.15750