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[Saved myocardium in acute ST-segment elevation myocardial infarction post-reperfusion: Analysis by cardiac magnetic resonance].

Authors :
Díaz-Navarro R
Sáez T
Peirano F
González DS
Source :
Revista medica de Chile [Rev Med Chil] 2023 Sep; Vol. 151 (9), pp. 1164-1176.
Publication Year :
2023

Abstract

Objective: To quantify by cardiovascular magnetic resonance the salvaged myocardium in the myocardium supplied by the infarct-related artery in reperfused and non-reperfused patients with a first ST-segment elevation myocardial infarction (STEMI).<br />Patients and Method: Twenty-five patients with a first STEMI (non-reperfused, ten patients; thrombolysis, ten patients; primary angioplasty, five patients) underwent cardiac magnetic resonance imaging 3 to 6 days after coronary angiography. Myocardial salvage and myocardial salvage index were quantified.<br />Results: Peak troponin values were lower in patients with primary angioplasty than in thrombolysis and non-reperfused patients (14,1 ng/ mL versus 515,4 ng/mL and 123,1 ng/mL, respectively; p < 0,007) and smaller infarct size (14,1 g versus 31,2 g and 31,5 g, respectively; p < 0,003). Myocardial salvage mass and myocardial salvage index were higher in patients with primary angioplasty than in thrombolysis and non-reperfused patients (27,4 g versus 4,7 g and 2,1 g, respectively; p < 0,003) and (65,2% versus 14,9% and 6,6%, respectively; p < 0,0001).<br />Conclusions: The results of this study indicate the need to reassess the performance of coronary angioplasty and stent implantation in patients with a first STEMI, thrombolysis, and non-thrombolysis without prior myocardial viability studies. Cardiac magnetic resonance allows the quantification of salvaged myocardium and could be considered an emerging clinical application for the early evaluation of myocardial viability.

Details

Language :
Spanish; Castilian
ISSN :
0717-6163
Volume :
151
Issue :
9
Database :
MEDLINE
Journal :
Revista medica de Chile
Publication Type :
Academic Journal
Accession number :
39093153
Full Text :
https://doi.org/10.4067/s0034-98872023000901164