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A rare case of extragastrointestinal stromal tumor of vocal cord - case report.

Authors :
Chahar OS
Br L
Raina S
Singh KD
Tripathi S
Singh O
Bisht N
Source :
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India [Indian J Otolaryngol Head Neck Surg] 2024 Aug; Vol. 76 (4), pp. 3625-3628. Date of Electronic Publication: 2024 Apr 16.
Publication Year :
2024

Abstract

Gastrointestinal stromal tumors (GISTs) are the mesenchymal tumors of the gastrointestinal tract. Extra Gastrointestinal stromal tumors (EGISTs) are rare neoplasms that occur outside the gastrointestinal tract [1]. Miettinen et al. [2] described the first EGIST in 1999. EGIST accounts for 10% of all GISTs [3]. The main distinction between GIST and EGIST is the site of origin of the primary tumor, as GIST occurs throughout the GI tract, from the esophagus to the anus, whereas EGIST is a tumor without any connection with the intestinal wall and are reported in the retroperitoneum, mesentery, and omentum [4]. Hu et al. [5] reported a first case report of EGIST of larynx.We present a second case report of Extra-gastrointestinal stromal tumor of larynx a 47-year-old male reported to ENT Department Command Hospital Central Command Lucknow with complaints of Hoarseness. On examination found to have right vocal cord growth for which he underwent excision of right vocal cord growth. Histopathological examination showed typical of a spindle-cell GIST, showing strong immunoreactivity for CD 117, DOG1, Vimentin and CD 99. 6 months follow up post surgery with no recurrence.<br />Competing Interests: Conflict of interestThere are no conflicts of interest.<br /> (© Association of Otolaryngologists of India 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)

Details

Language :
English
ISSN :
2231-3796
Volume :
76
Issue :
4
Database :
MEDLINE
Journal :
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
Publication Type :
Academic Journal
Accession number :
39130319
Full Text :
https://doi.org/10.1007/s12070-024-04652-5