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Ten-year trends in characteristics, management and outcomes of patients admitted with cardiogenic shock in the ACTION-SHOCK cohort.
- Source :
-
Archives of cardiovascular diseases [Arch Cardiovasc Dis] 2024 Aug 06. Date of Electronic Publication: 2024 Aug 06. - Publication Year :
- 2024
- Publisher :
- Ahead of Print
-
Abstract
- Background: The ACTION-SHOCK registry offers a decade-long perspective on patients admitted with cardiogenic shock (CS).<br />Aims: To assess trends in the management and outcomes of patients with CS over 10 years.<br />Methods: Trends in the characteristics, management and outcomes of patients with CS admitted into the cardiac intensive care unit of Pitié-Salpêtrière hospital from 2011 to 2020 were analysed. Short-term outcomes included in-hospital mortality, heart transplantation or ventricular assist device. Long-term outcomes were all-cause death or readmission for acute heart failure at 1 year.<br />Results: Over a 10-year period, data from 700 patients with CS (median [interquartile range] age 61 [50-72] years; 73% of men) were analysed. The proportion of CS related to acute myocardial infarction decreased (from 45% in 2011-2012 to 27% in 2019-2020) while the proportions related to chronic coronary syndrome (18% to 23%) and non-ischaemic cardiomyopathies (37 to 51%) increased (P<0.01). The use of rescue extracorporeal membrane oxygenation remained stable (19 to 14%) and intra-aortic balloon pump use decreased (22% to 7%) (P<0.01). In-hospital mortality remained stable (27 to 29%) as did the proportions of patients discharged after transplantation (17 to 14%) or with a durable ventricular assist device (2 to 4%). Among patients discharged alive, death or readmission for acute heart failure at 1 year remained high (37 to 47%).<br />Conclusion: CS remained associated with a poor prognosis over the last decade. There are significant unmet needs in the management strategies of patients with CS.<br /> (Copyright © 2024 Elsevier Masson SAS. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1875-2128
- Database :
- MEDLINE
- Journal :
- Archives of cardiovascular diseases
- Publication Type :
- Academic Journal
- Accession number :
- 39153876
- Full Text :
- https://doi.org/10.1016/j.acvd.2024.07.059