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Radical cystectomy with stentless urinary diversion: A systematic review and meta-analysis of comparative studies.

Authors :
Veccia A
Brusa D
Treccani L
Malandra S
Serafin E
Costantino S
Cianflone F
Ditonno F
Montanaro F
Fumanelli F
Ferro M
Mazzon G
Autorino R
Bertolo R
Antonelli A
Source :
Urologic oncology [Urol Oncol] 2025 Jan; Vol. 43 (1), pp. 54-60. Date of Electronic Publication: 2024 Aug 20.
Publication Year :
2025

Abstract

Purpose: To systematically compare the evidence about surgical outcomes, postoperative complications, and sequelae of Radical cystectomy with urinary diversion with or without stent placement.<br />Material and Methods: A literature search was performed through PubMed, Scopus®, and Web of Science up to December 2023 in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. The study protocol was registered in PROSPERO (CRD 42023492384), and the research question was formulated according to the PICOs model. Three comparative studies were identified, 2 randomized and 1 prospective coming from a randomized cohort.<br />Results: The stent group showed higher odds of postoperative major complications (OR 3.00 - 95%CI 1.06; 8.52; P = 0.04) than the stentless group. There was no statistically significant difference between the 2 groups regarding 30-day readmission (P = 0.06), postoperative uretero-ileal anastomotis stricture (UIAS) (P = 0.09), postoperative uretero-ileal anastomotis leak (UIAL) (P = 0.20), postoperative urinary tract infections (UTIs) (P = 0.08), and postoperative ureteral obstruction (P = 0.35). No statistically significant difference between the 2 groups was found regarding UIAS management in terms of ureteral reimplantation (P = 0.28) or dilatation (P = 0.36).<br />Conclusions: Our pooled data analysis shows no statistically significant difference between stentless and stented urinary diversion after radical cystectomy. Stentless could be a reasonable choice when performing diversion during radical cystectomy.<br />Competing Interests: Declaration of competing interest I declare there are no conflicts of interest regarding any author.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1873-2496
Volume :
43
Issue :
1
Database :
MEDLINE
Journal :
Urologic oncology
Publication Type :
Academic Journal
Accession number :
39164149
Full Text :
https://doi.org/10.1016/j.urolonc.2024.06.025