Functional Design Analysis of Two Current Extended-Depth-of-Focus Intraocular Lenses.

Purpose: To evaluate the differences between two extended depth-of-focus intraocular lenses, the Alcon IQ Vivity and the Bausch & Lomb LuxSmart and to compare them with a simple monofocal lens, the Alcon IQ, using a simulation-based approach.
Methods: A mathematical lens model was created for each lens type based on a measured surface geometry. The lens model was then used in a raytracer to calculate a refractive power map of the lens and a ray propagation image for the focal zone.
Results: The simulations confirm the enhanced depth of focus of these two lenses. There are apparent differences between the models. For the Vivity, more light is directed into the far focus in low light conditions, whereas the LuxSmart behaves more pupil independent and prioritizes intermediate vision.
Conclusions: The simulation-based approach was effective in evaluating and comparing the design aspects of these lenses. It can be positioned as a valuable third tool for lens characterization, complementing in vivo studies and in vitro measurements.
Translational Relevance: With this approach not only focusing on the resulting optical performance, but the underlying functional mechanisms, it paves the way forward for a better adaptation to the individual needs and preferences of patients.