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Why does a cell function? New arguments in favor of quantum effects.

Authors :
Melkikh AV
Source :
Bio Systems [Biosystems] 2024 Nov; Vol. 245, pp. 105311. Date of Electronic Publication: 2024 Aug 20.
Publication Year :
2024

Abstract

In this study, the complexities of intracellular processes have been analyzed, including DNA folding, alternative splicing, mitochondrial function, and enzyme transport in lysosomes. Based on a previously proposed hypothesis (Levinthal's generalized paradox), a conclusion is made that all abovementioned processes cannot be realized with sufficient accuracy and in a realistic timeframe within the framework of classical physics. It is unclear why the cell functions at all. For the cell to function, its internal environment must be highly structured. In this regard, the cell shares similarities with computational devices (computers). In this study, quantum models of interactions between biologically important molecules were constructed, taking into account the long-range effects. One significant aspect of these models is the special role of the phase of the wavefunction, which serves as a controlling parameter. Experiments have been proposed that may confirm or refute these models.<br />Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1872-8324
Volume :
245
Database :
MEDLINE
Journal :
Bio Systems
Publication Type :
Academic Journal
Accession number :
39173899
Full Text :
https://doi.org/10.1016/j.biosystems.2024.105311