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Comparison of clinical parameters of peri-implantitis and parameters related to tissue macrophage sensitization on TiO 2 .

Comparison of clinical parameters of peri-implantitis and parameters related to tissue macrophage sensitization on TiO 2 .

Authors :
Sahrmann P
Tartsch J
Schmidlin PR
Source :
Clinical oral investigations [Clin Oral Investig] 2024 Aug 25; Vol. 28 (9), pp. 499. Date of Electronic Publication: 2024 Aug 25.
Publication Year :
2024

Abstract

Objective: Dental implants show impressive survival and like rates, but peri-implantitis is a frequent inflammatory disease which affects the implant-surrounding tissues. While biofilms on the implant surface is considered its etiologic reason, several risk factors determine the pace of progression of peri-implant bone loss. Some risk factors are generally accepted while others are still unconfirmed and a matter of ongoing discussion. Among the latter, tissue macrophage sensitization on TiO <subscript>2</subscript> has gained scientific interest in recent years. The aim of the present case-control study was to test for potential associations between clinically manifest peri-implantitis and MS related parameters.<br />Materials and Methods: In patients with implants affected by peri-implantitis in the test group and healthy implants in the control group clinical parameters (peri-implant pocket depths (PPD) and bleeding on probing (BOP) were measured. Samples of aMMP-8 were taken from the entrance of the peri-implant sulcus and bacterial samples were collected from the sulcus. Blood samples were obtained from the basilic vein to assess MA-related laboratory parameters. Potential correlations between clinical and laboratory parameters were tested by multiple regression (pā€‰<ā€‰0.05).<br />Results: No statistically significant correlations were found between clinical or bacteriological findings and laboratory parameters were found.<br />Conclusions: Based on the findings of this study elevated MA-related laboratory parameters do not appear to be linked to peri-implantitis.<br />Clinical Relevance: Sensitization on TiO <subscript>2</subscript> is not associated with clinical symptoms of peri-implantitis.<br /> (© 2024. The Author(s).)

Details

Language :
English
ISSN :
1436-3771
Volume :
28
Issue :
9
Database :
MEDLINE
Journal :
Clinical oral investigations
Publication Type :
Academic Journal
Accession number :
39182209
Full Text :
https://doi.org/10.1007/s00784-024-05880-3