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Comparison of clinical parameters of peri-implantitis and parameters related to tissue macrophage sensitization on TiO 2 .
Comparison of clinical parameters of peri-implantitis and parameters related to tissue macrophage sensitization on TiO 2 .
- Source :
-
Clinical oral investigations [Clin Oral Investig] 2024 Aug 25; Vol. 28 (9), pp. 499. Date of Electronic Publication: 2024 Aug 25. - Publication Year :
- 2024
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Abstract
- Objective: Dental implants show impressive survival and like rates, but peri-implantitis is a frequent inflammatory disease which affects the implant-surrounding tissues. While biofilms on the implant surface is considered its etiologic reason, several risk factors determine the pace of progression of peri-implant bone loss. Some risk factors are generally accepted while others are still unconfirmed and a matter of ongoing discussion. Among the latter, tissue macrophage sensitization on TiO <subscript>2</subscript> has gained scientific interest in recent years. The aim of the present case-control study was to test for potential associations between clinically manifest peri-implantitis and MS related parameters.<br />Materials and Methods: In patients with implants affected by peri-implantitis in the test group and healthy implants in the control group clinical parameters (peri-implant pocket depths (PPD) and bleeding on probing (BOP) were measured. Samples of aMMP-8 were taken from the entrance of the peri-implant sulcus and bacterial samples were collected from the sulcus. Blood samples were obtained from the basilic vein to assess MA-related laboratory parameters. Potential correlations between clinical and laboratory parameters were tested by multiple regression (pā<ā0.05).<br />Results: No statistically significant correlations were found between clinical or bacteriological findings and laboratory parameters were found.<br />Conclusions: Based on the findings of this study elevated MA-related laboratory parameters do not appear to be linked to peri-implantitis.<br />Clinical Relevance: Sensitization on TiO <subscript>2</subscript> is not associated with clinical symptoms of peri-implantitis.<br /> (© 2024. The Author(s).)
Details
- Language :
- English
- ISSN :
- 1436-3771
- Volume :
- 28
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Clinical oral investigations
- Publication Type :
- Academic Journal
- Accession number :
- 39182209
- Full Text :
- https://doi.org/10.1007/s00784-024-05880-3