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Waste-Derived Copper Flakes for Solvent-Free Reductive Acetamidation of Nitroarenes.
- Source :
-
Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2024 Sep 10; Vol. 40 (36), pp. 18961-18967. Date of Electronic Publication: 2024 Aug 28. - Publication Year :
- 2024
-
Abstract
- Herein, waste-derived copper (Cu) flakes have been used as heterogeneous catalysts for the solvent-free and one-pot reductive acetamidation of nitroarenes. Metallic copper flakes (f-ZCu) were isolated from waste copper Cu scrap/flakes/turnings generated after the grinding and cutting (from the Cu industries). f-ZCu is being used to synthesize acetanilide with a considerable yield (∼82%) in one-step and solvent-free conditions within a reaction time of 6 h. Moreover, the same procedure is also being utilized for producing various substrates (9), including the gram-scale synthesis of the well-known important antipyretic drug, i.e., paracetamol. The plausible mechanism for the reaction was also proposed based on the spectroscopic analyses of spent f-ZCu.
Details
- Language :
- English
- ISSN :
- 1520-5827
- Volume :
- 40
- Issue :
- 36
- Database :
- MEDLINE
- Journal :
- Langmuir : the ACS journal of surfaces and colloids
- Publication Type :
- Academic Journal
- Accession number :
- 39196909
- Full Text :
- https://doi.org/10.1021/acs.langmuir.4c01639