Pancreas Cyst Diagnosis and Advances in Cyst Fluid Analysis.

Authors :: Pollini T
Todeschini L
Maker AV
Source :: The Surgical clinics of North America [Surg Clin North Am] 2024 Oct; Vol. 104 (5), pp. 965-974. Date of Electronic Publication: 2024 Apr 23.
Publication Year :: 2024
Abstract: Pancreatic Cystic Neoplasms (PCN) represent a diverse group of tumors, some of which may progress to pancreatic cancer. Considering their high prevalence in the general population, the development of reliable biomarkers is crucial. The ideal biomarker will accurately diagnose the subtype of PCN and assess the risk of high-grade dysplasia or invasive cancer. Cyst fluid analysis has emerged as a promising approach to accomplish this goal, yet no single marker has yet gained unanimous support for routine inclusion in PCN evaluation.<br />Competing Interests: Disclosure A.V. Maker is an inventor of record on the following pending or issued patent: WO2018183603A1 (PCT/US2018/025,027). T. Pollini and L. Todeschini have no conflict of interest. Funding Authors acknowledge the support of the Inner Child Foundation and the Shorenstein Foundation.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)