Lipid-Laden Floret-Like Multinucleated Giant Cells: A Novel Histopathologic Observation in Rhinophyma.

Authors :: Daruish M
Patalay R
Calonje E
Stefanato CM
Source :: The American Journal of dermatopathology [Am J Dermatopathol] 2024 Nov 01; Vol. 46 (11), pp. 746-750. Date of Electronic Publication: 2024 Sep 17.
Publication Year :: 2024
Abstract: Abstract: Rhinophyma is the advanced stage of rosacea and manifests clinically with disfigurement of the nose. The histopathology has been classified into classical and severe types. We studied the clinicopathological characteristics of 8 cases with the diagnosis of rhinophyma. In 5 of 9 specimens, floret-like multinucleated giant cells containing lipid were identified. This finding, to the best of our knowledge, has not been previously described.<br />Competing Interests: The authors declare no conflicts of interest.<br /> (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Subjects :: Humans
Male
Female
Middle Aged
Aged
Adult
Lipids analysis
Rhinophyma pathology
Giant Cells pathology

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