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Chalcone derived bis-organosilane and its magnetic nanoparticles: Unveiling precision in selective Cu(II) ion detection and elucidating biocompatibility.
- Source :
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2025 Jan 15; Vol. 325, pp. 125124. Date of Electronic Publication: 2024 Sep 11. - Publication Year :
- 2025
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Abstract
- The escalating concern regarding the adverse effects of metal ion toxicity on both human health and environmental ecosystems necessitates the development of efficient detection methodologies. This study presents a focused investigation on the selective and sensitive detection of Cu(II) ions employing hybrid magnetic nanoparticles derived from chalcone-based bis-organosilane. These nanoparticles exhibit a notably low detection limit in the nano-scale range, rendering the sensor highly sensitive to Copper(II) ion detection while maintaining robust anti-interference capabilities, even in the presence of diverse metal ions. Real sample analysis confirms the sensor's efficacy in detecting Cu(II) ions below WHO-prescribed levels. Computational analyses reveal molecular interactions and biological activities, including potent antibacterial and antioxidant properties, suggesting promising applications. Furthermore, the biological effectiveness of chalcone-derived bis-organosilane is investigated, unveiling notable antibacterial efficacy and also exhibiting potential as a scavenger of free radicals, indicating promising applications in both antibacterial and antioxidant domains.<br />Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024 Elsevier B.V. All rights reserved.)
- Subjects :
- Antioxidants pharmacology
Antioxidants chemistry
Antioxidants analysis
Humans
Chalcone chemistry
Chalcone pharmacology
Biocompatible Materials chemistry
Biocompatible Materials pharmacology
Ions analysis
Microbial Sensitivity Tests
Copper analysis
Copper chemistry
Silanes chemistry
Magnetite Nanoparticles chemistry
Anti-Bacterial Agents pharmacology
Anti-Bacterial Agents analysis
Anti-Bacterial Agents chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1873-3557
- Volume :
- 325
- Database :
- MEDLINE
- Journal :
- Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
- Publication Type :
- Academic Journal
- Accession number :
- 39303335
- Full Text :
- https://doi.org/10.1016/j.saa.2024.125124