Canine exfoliative cutaneous lupus erythematosus in two mixed breed littermates.

Authors :: Dumitrache MO
Ursache AL
Toma C
Negoescu A
Rietmann SJ
Leeb T
Cadiergues MC
Source :: Veterinary dermatology [Vet Dermatol] 2025 Feb; Vol. 36 (1), pp. 99-103. Date of Electronic Publication: 2024 Sep 30.
Publication Year :: 2025
Abstract: Canine exfoliative cutaneous lupus erythematosus (ECLE) is the rarest variant of cutaneous lupus in dogs and has strong breed predilections. This report presents the clinical, histopathological and immunohistochemical features of two ECLE cases in mixed breed littermates and confirms the expected genetic mutation. A therapeutic response to oclacitinib also is documented.<br /> (© 2024 ESVD and ACVD.)

Subjects :: Animals
Dogs
Female
Male
Sulfonamides therapeutic use
Pyrimidines
Dog Diseases genetics
Dog Diseases pathology
Dog Diseases drug therapy
Lupus Erythematosus, Cutaneous veterinary
Lupus Erythematosus, Cutaneous genetics
Lupus Erythematosus, Cutaneous drug therapy
Lupus Erythematosus, Cutaneous pathology

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