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How condensed are mitotic chromosomes?

Authors :
Konishi HA
Funabiki H
Source :
The Journal of cell biology [J Cell Biol] 2024 Nov 04; Vol. 223 (11). Date of Electronic Publication: 2024 Oct 14.
Publication Year :
2024

Abstract

Chromosomes undergo dramatic compaction during mitosis, but accurately measuring their volume has been challenging. Employing serial block face scanning electron microscopy, Cisneros-Soberanis et al. (https://doi.org/10.1083/jcb.202403165) report that mitotic chromosomes compact to a nucleosome concentration of ∼760 µM.<br /> (© 2024 Konishi and Funabiki.)

Details

Language :
English
ISSN :
1540-8140
Volume :
223
Issue :
11
Database :
MEDLINE
Journal :
The Journal of cell biology
Publication Type :
Academic Journal
Accession number :
39400309
Full Text :
https://doi.org/10.1083/jcb.202409044