Multifocal vitelliform lesions associated with mitochondrial retinopathy.

Authors :: Battaglia Parodi M
Antropoli A
Bianco L
Arrigo A
Del Fabbro S
Carrera P
Spiga I
Catania A
Lamperti C
Bandello F
Mansour A
Source :: American journal of ophthalmology case reports [Am J Ophthalmol Case Rep] 2024 Oct 02; Vol. 36, pp. 102181. Date of Electronic Publication: 2024 Oct 02 (Print Publication: 2024).
Publication Year :: 2024
Abstract: Purpose: To report a case of multifocal vitelliform lesions in a patient affected by metabolic encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) with the m.3243A>G variant.<br />Observations: A 37-year-old woman affected by MELAS was referred to our center for progressive vision deterioration. On fundus examination, she presented bilateral macular atrophy associated in the left eye with neurosensory detachment, along with several bilateral vitelliform lesions close to the vascular arcades. We describe the dynamic evolution of the vitelliform lesions, which could either enlarge and coalesce or undergo atrophic evolution.<br />Conclusions: Mitochondrial retinopathy due to the m.3243A>G variant can be associated with multifocal vitelliform lesions.<br />Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (© 2024 The Authors. Published by Elsevier Inc.)