Modulating the photolysis of aryl azides in a supramolecular host to develop photoactivatable fluorophores.

Authors :: Qiu X
Pohl E
Jung A
Cai Q
Su H
Fuhr O
Schepers U
Bräse S
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Oct 16. Date of Electronic Publication: 2024 Oct 16.
Publication Year :: 2024
Publisher :: Ahead of Print
Abstract: Photolysis of aryl azides is a convenient method to approach more functionalized systems in chemical biology. Here, we present a set of photoactivatable aryl azides that undergo controlled reaction pathways within the cucurbit[7]uril (CB7) cavity upon photolysis. The fluorescence turn-on process is utilized for bioimaging.

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