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Insights from qualitative and bifurcation analysis of COVID-19 vaccination model in Bangladesh.

Authors :
Kuddus MA
Mohiuddin M
Paul AK
Rahman A
Source :
PloS one [PLoS One] 2024 Nov 01; Vol. 19 (11), pp. e0312780. Date of Electronic Publication: 2024 Nov 01 (Print Publication: 2024).
Publication Year :
2024

Abstract

The unprecedented global impact of the 2019 coronavirus disease (COVID-19) has necessitated a comprehensive understanding of its transmission dynamics and control measures. In this study, we present a detailed analysis of a COVID-19 vaccination model tailored to the context of Bangladesh, incorporating dual-dose vaccination strategies. By employing qualitative and bifurcation analysis techniques, we investigate the equilibrium points, effective reproduction number (R0), and critical thresholds that influence the prevalence and control of COVID-19 in the region. Our findings reveal insights into the effectiveness of vaccination programs and provide a framework for developing targeted control plans. Through a rigorous examination of model parameters and sensitivity analysis, we identify key factors driving COVID-19 transmission dynamics, emphasizing the significance of vaccination rates and other critical parameters. The validation of our model against real-world data underscores its utility in informing evidence-based decision-making for managing the COVID-19 pandemic in Bangladesh and beyond.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright: © 2024 Kuddus et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Details

Language :
English
ISSN :
1932-6203
Volume :
19
Issue :
11
Database :
MEDLINE
Journal :
PloS one
Publication Type :
Academic Journal
Accession number :
39485754
Full Text :
https://doi.org/10.1371/journal.pone.0312780