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AIntibody: an experimentally validated in silico antibody discovery design challenge.

Authors :
Erasmus MF
Spector L
Ferrara F
DiNiro R
Pohl TJ
Perea-Schmittle K
Wang W
Tessier PM
Richardson C
Turner L
Kumar S
Bedinger D
Sormanni P
Fernández-Quintero ML
Ward AB
Loeffler JR
Swanson OM
Deane CM
Raybould MIJ
Evers A
Sellmann C
Bachas S
Ruffolo J
Nastri HG
Ramesh K
Sørensen J
Croasdale-Wood R
Hijano O
Leal-Lopes C
Shahsavarian M
Qiu Y
Marcatili P
Vernet E
Akbar R
Friedensohn S
Wagner R
Kurella VB
Malhotra S
Kumar S
Kidger P
Almagro JC
Furfine E
Stanton M
Graff CP
Villalba SD
Tomszak F
Teixeira AAR
Hopkins E
Dovner M
D'Angelo S
Bradbury ARM
Source :
Nature biotechnology [Nat Biotechnol] 2024 Nov; Vol. 42 (11), pp. 1637-1642.
Publication Year :
2024

Abstract

Competing Interests: Competing interests L.S., F.F., R.D., T.J.P., K.P.-S., S.D., M.F.E. and A.R.M.B. are employees of Specifica, an IQVIA business. O.H., C.L.-L. and Y.Q. are employees of Sanofi. H.G.N. and K.R. are employees of Incyte and stockholders. M. Shahsavarian is an employee of Eli Lilly. D.B. is an employee of Carterra. R.W. is an employee of Bonito Biosciences. C.M.D. discloses membership of the Scientific Advisory Board of Fusion Antibodies and AI proteins. P.M.T. is a member of the scientific advisory board for Nabla Bio, Aureka Biotechnologies, and Dualitas Therapeutics. P.M., E.V. and R.A. are employees of Novo Nordisk A/S. J.S. is an employee of OpenEye, Cadence Molecular Sciences. R.C.W. is an employee of AstraZeneca. A.E. and C.S. are employees of Merck Healthcare KGaA. S.B. is an employee of Evolutionary Scale. J.R. is an employee of Profluent Bio. S.F. is an employee of Alloy Therapeutics. V.B.K., S.M. and S.K. are employees of Takeda. P.K. is an employee of Cradle Bio. J.C.A. is an employee of GlobalBio. E.F., M. Stanton and C.P.G. are employees of Mosaic Biosciences. S.D.V. and F.T. are employees of Bayer A.G. All other authors declare no competing interests.

Details

Language :
English
ISSN :
1546-1696
Volume :
42
Issue :
11
Database :
MEDLINE
Journal :
Nature biotechnology
Publication Type :
Editorial & Opinion
Accession number :
39496931
Full Text :
https://doi.org/10.1038/s41587-024-02469-9