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Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network.

Authors :
Bucayu RFT
Boge CLK
Yildirim I
Avilés-Robles M
Vora SB
Berman DM
Sharma TS
Sung L
Castagnola E
Palazzi DL
Danziger-Isakov L
Yin DE
Roilides E
Maron G
Tribble AC
Soler-Palacin P
López-Medina E
Romero J
Belani K
Arrieta AC
Carlesse F
Nolt D
Halasa N
Dulek D
Rajan S
Muller WJ
Ardura MI
Pong A
Gonzalez BE
Salvatore CM
Huppler AR
Aftandilian C
Abzug MJ
Chakrabarti A
Green M
Lutsar I
Knackstedt ED
Johnson SK
Steinbach WJ
Fisher BT
Wattier RL
Source :
Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2024 Dec 30; Vol. 13 (12), pp. 633-638.
Publication Year :
2024

Abstract

Of 319 children with invasive candidiasis, 67 (21%) transitioned from intravenous to enteral antifungal therapy. Eight (12%) transitioned back to intravenous antifungal therapy, one due to perceived treatment failure defined by clinical progression or worsening. Global treatment response at study completion was successful in 66 participants who transitioned to enteral therapy.<br /> (© The Author(s) 2024. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Details

Language :
English
ISSN :
2048-7207
Volume :
13
Issue :
12
Database :
MEDLINE
Journal :
Journal of the Pediatric Infectious Diseases Society
Publication Type :
Academic Journal
Accession number :
39513400
Full Text :
https://doi.org/10.1093/jpids/piae116