Analysis of the efficacy of different amounts of parathyroid grafts in the treatment of secondary hyperparathyroidism.

Purpose: This study compares the efficacy of two different ranges of parathyroid transplantation weights with the aim of determining a preferable range for transplantation weight.
Methods: From May 2018 to June 2023, 79 patients underwent total parathyroidectomy with autotransplantation. Demographic data, symptoms, and pre- or postoperative biochemical indicators were compared between two different ranges of parathyroid transplantation weights.
Results: All 79 surgeries were successful, with a total of 316 parathyroid glands reported among the patients. The patients were diagnosed with parathyroid hyperplasia. Postoperatively, itching, bone pain, and muscle weakness disappeared, while serum parathyroid hormone and phosphate levels significantly decreased. With an average follow-up of 12 months, no transplant-dependent recurrence was observed.
Conclusion: Parathyroid transplantation with a weight of 30-50 mg is a feasible, safe, and effective surgical approach.
Competing Interests: Declarations Ethics approval and consent to participate The study was conducted following the principles stated in the Declaration of Helsinki. This study is an observational, retrospective research. Patients’ written informed consent for using health data was obtained before operation. The experimental protocol approved by the ethics committee of Liaoyang Central Hospital (ethical number:2024080107). Consent for publication Not applicable. Clinical trial number Not applicable. Competing interests The authors declare no competing interests.
(© 2024. The Author(s).)