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Autophagy-dependent ferroptosis mediates multiple sclerosis.

Authors :
Tang D
Kang R
Klionsky DJ
Source :
Autophagy [Autophagy] 2025 Feb; Vol. 21 (2), pp. 257-259. Date of Electronic Publication: 2024 Nov 22.
Publication Year :
2025

Abstract

A recent paper published in Cell by Woo et al. reported that autophagy-dependent ferroptosis mediated by STING1 is involved in neuronal death associated with multiple sclerosis (MS). This research broadens our understanding of the pathogenesis of MS and opens new avenues for therapeutic interventions.

Details

Language :
English
ISSN :
1554-8635
Volume :
21
Issue :
2
Database :
MEDLINE
Journal :
Autophagy
Publication Type :
Academic Journal
Accession number :
39577841
Full Text :
https://doi.org/10.1080/15548627.2024.2419112