Estimation of population-specific values of theta for PowerPlex Y23 profiles.

Authors :: Buckleton JS
Hall TO
Bright JA
Yung MC
Goudet J
Kruijver M
Weir BS
Source :: Forensic science international. Genetics [Forensic Sci Int Genet] 2025 Feb; Vol. 75, pp. 103175. Date of Electronic Publication: 2024 Nov 16.
Publication Year :: 2025
Abstract: We examine 31,011 PPY23 profiles at the population, metapopulation and world levels. Most haplotypes appear only once but a few have higher counts, including a set of 23 matching profiles in Delhi, India and a set of 16 matching profiles in Burkina Faso with one additional matching American African profile. We estimate F <subscript>ST</subscript> values to be used as "theta" (θ) in match probability calculations, following the method we used in our earlier survey of autosomal STR data. Match probability estimates using Fˆ <subscript>ST</subscript> or the κ method of Brenner for a previously unseen profile are similar but differ for any profile previously seen.<br />Competing Interests: Declaration of Competing Interest The authors have no competing interests to declare.<br /> (Copyright © 2024 Elsevier B.V. All rights reserved.)