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[Distribution of iodinated antibodies to the human organ-specific intestinal antigen in athymic mice with heterotransplanted tumors].
- Source :
-
Meditsinskaia radiologiia [Med Radiol (Mosk)] 1986 Apr; Vol. 31 (4), pp. 26-9. - Publication Year :
- 1986
-
Abstract
- 131I labeled rabbit antibodies to the human epithelial intestinal antigen beta 1-MA was administered intravenously to nude mice together with human tumor grafts: colon cancer (CC), breast cancer, Ewing's sarcoma and hepatoma. Antibodies to beta 1-MA were selectively accumulated in CC only, excluding the other tumors. Iodinated nonspecific rabbit IgG in mice with CC were distributed like antibodies to beta 1-MA in the body of mice with control heterografts. A conclusion was made of the promising use of labeled antibodies to beta 1-MA in radioimmuno-scintigraphy of CC and its metastases.
Details
- Language :
- Russian
- ISSN :
- 0025-8334
- Volume :
- 31
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Meditsinskaia radiologiia
- Publication Type :
- Academic Journal
- Accession number :
- 3959807