Successfully Managed Toxic Megacolon Due to Clostridium difficile Infection in a Pheochromocytoma Patient Complicated by Cardiogenic and Septic Shock: A Case Report.

In recent years, there has been a significant rise in both the frequency and severity of Clostridium difficile colitis. This infection presents a broad clinical spectrum, ranging from asymptomatic colonization to severe fulminant colitis, which often requires urgent surgical intervention. The failure of medical treatments and the development of toxic megacolon typically necessitate surgery, though it is associated with high mortality rates. In this case, we successfully managed a rare instance of fulminant colitis in a pheochromocytoma patient with complicated cardiogenic and septic shock through conservative therapy, utilizing the standard vancomycin-metronidazole combination, supplemented with rifaximin.
Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Ethics Committee of the American Hospital Tbilisi issued approval 4. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
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