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Antiviral immunity lassoed down by excess RNA.
- Source :
-
The Journal of experimental medicine [J Exp Med] 2025 Jan 06; Vol. 222 (1). Date of Electronic Publication: 2024 Dec 06. - Publication Year :
- 2025
-
Abstract
- Two complementary works by Chan et al. (https://doi.org/10.1084/jem.20231725), and Ru et al. (https://doi.org/10.1084/jem.20240010), identify defective RNA processing as the root cause of impaired antiviral immunity against SARS-CoV2 in the human brainstem. These studies provide molecular insight into virus-associated severe brainstem encephalitis through PKR inactivation.<br /> (© 2024 Valeri and Kajaste-Rudnitski.)
Details
- Language :
- English
- ISSN :
- 1540-9538
- Volume :
- 222
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Journal of experimental medicine
- Publication Type :
- Academic Journal
- Accession number :
- 39641763
- Full Text :
- https://doi.org/10.1084/jem.20241743