Angiotensin II administration in severe thrombocytopenia and chronic venous thrombosis: A case report.

Background: The initial trials on angiotensin II (AT II) administration indicated a high incidence of thrombocytopenia and thrombosis, as well as a positive correlation between hyperreninemia and response to the medication.
Case Summary: We describe a case of a patient presenting with catecholamine resistant septic shock, thrombocytopenia, deep vein thrombosis, and normal renin concentration who responded immediately to AT II treatment. We observed no worsening of thrombocytopenia and no progression of thrombosis or additional thromboses during treatment.
Conclusion: Our case underscores the need for individualized assessment of patients for potential therapy with AT II.
Competing Interests: Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
(©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)