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Directed stochasticity: Building biomolecular condensates in the right place.
- Source :
-
The Journal of cell biology [J Cell Biol] 2025 Jan 06; Vol. 224 (1). Date of Electronic Publication: 2024 Dec 24. - Publication Year :
- 2025
-
Abstract
- Controlling biomolecular condensate formation within the nucleus is critical for genome function. In this issue, Xu et al. (https://doi.org/10.1083/jcb.202401036) report that KPNA3 promotes histone locus body formation and expression of replication-dependent histone genes by both importing NPAT into the nucleus and preventing NPAT condensation from improperly occurring in the cytoplasm.<br /> (© 2024 Geisler et al.)
Details
- Language :
- English
- ISSN :
- 1540-8140
- Volume :
- 224
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Journal of cell biology
- Publication Type :
- Academic Journal
- Accession number :
- 39718563
- Full Text :
- https://doi.org/10.1083/jcb.202412035