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Hyperthyroidism crisis and complex pancytopenia: A case report.

Authors :
Lei X
Leng W
Long M
Xie L
Chen L
Source :
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences [Zhong Nan Da Xue Xue Bao Yi Xue Ban] 2024 Jul 28; Vol. 49 (7), pp. 1089-1094.
Publication Year :
2024

Abstract

Antithyroid drugs can cause neutropenia or agranulocytosis, rarely pancytopenia in hyperthyroidism therapy. The treatment is difficult and lethality is high when granulocytopenia or pancytopenia combined with hyperthyroidism crisis. First Affiliated Hospital of Army Medical University treated a patient who had pancytopenia caused by methimazole with systemic lupus erythematosus, secondary hyperthyroidism crisis and agranulocytosis.We gave the reasonable treatment in time, such as anti-infection, stimulating granulocyopoiesis, compound iodine solution to control thyroid function, controlled the disease effectively and saved the patient's life. Early detection and identification of possible causes of pancytopenia and dynamic adjustment of treatment plan show great significance for patients with hyperthyroidism and severe pancytopenia.

Details

Language :
English; Chinese
ISSN :
1672-7347
Volume :
49
Issue :
7
Database :
MEDLINE
Journal :
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Publication Type :
Academic Journal
Accession number :
39788497
Full Text :
https://doi.org/10.11817/j.issn.1672-7347.2024.240372