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Benign Lung Adenoma Mimicking an Adenocarcinoma With EML4-ALK Gene Fusion.

Authors :
Hyde JR
Kamangar E
Ladenheim AE
Cooke DT
Source :
Annals of thoracic surgery short reports [Ann Thorac Surg Short Rep] 2022 Oct 18; Vol. 1 (1), pp. 137-139. Date of Electronic Publication: 2022 Oct 18 (Print Publication: 2023).
Publication Year :
2022

Abstract

Bronchiolar adenoma is a benign neoplastic process thought to be derived from the bronchiolar epithelium. Particularly in small biopsy specimens, this entity can mimic lung cancer with important implications for management. We report the case of a 33-year-old man with a right upper lobe lung nodule, with initial biopsy identifying an adenocarcinoma with EML4-ALK gene fusion. After being considered for neoadjuvant targeted therapy trials, the patient underwent a lobectomy. On postoperative histologic evaluation, the patient was found to have a benign bronchiolar adenoma.<br /> (© 2022 Published by Elsevier Inc. on behalf of The Society of Thoracic Surgeons.)

Details

Language :
English
ISSN :
2772-9931
Volume :
1
Issue :
1
Database :
MEDLINE
Journal :
Annals of thoracic surgery short reports
Publication Type :
Academic Journal
Accession number :
39790518
Full Text :
https://doi.org/10.1016/j.atssr.2022.10.006