Fact or Myth? Black Patients Do Not Want to Participate in Clinical Trials.

Authors :: Mills K
Figueroa F
Knight R
Ekpo E
Lee LC
Baldo L
Xu C
Wang S
Adelman RM
Pemu P
Levin T
Shaukat A
Liu JJ
Source :: Clinical and translational gastroenterology [Clin Transl Gastroenterol] 2025 Jan 29. Date of Electronic Publication: 2025 Jan 29.
Publication Year :: 2025
Publisher :: Ahead of Print
Abstract: Objectives: To assess strategies for optimizing participation of underserved minorities in a blood-based early CRC detection test study (PREEMPT CRC; NCT04369053) at a hospital serving primarily Black patients.<br />Methods: Culturally sensitive, racially congruent research staff approached patients undergoing average-risk screening colonoscopy. Consent/study procedures were synchronized with clinical appointments. Enrolled and not-enrolled patient characteristics were compared. Recruitment was compared with other study sites.<br />Results: 247/509 eligible participants enrolled; most identified as Black (88.7%). No baseline characteristics were associated with participation. Recruitment was high compared to other sites (11th centile).<br />Conclusions: Recruitment barriers for Black individuals can be overcome when easy, culturally sensitive access is facilitated.<br /> (Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)