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PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention.

Authors :
Castleberry TJ
England DL
Fylstra BL
Stevens PM
Todd AE
Mandacina SA
Wurdeman SR
Source :
Journal of patient-reported outcomes [J Patient Rep Outcomes] 2025 Feb 10; Vol. 9 (1), pp. 17. Date of Electronic Publication: 2025 Feb 10.
Publication Year :
2025

Abstract

Background: Upper extremity physical function is an essential health domain in the rehabilitation care for patients with upper limb amputation or absence. The PROMIS-9 UE Physical Function short form is a recently established instrument designed for individuals with upper limb amputation or absence. The instrument's responsiveness to changes after receiving a prosthesis has not been investigated. The current study aimed to evaluate the ability of the PROMIS-9 UE to detect changes in bimanual (two-handed) functional capacity after patients' receipt of a prosthesis.<br />Methodology: A retrospective chart review was conducted on the longitudinal PROMIS-9 UE outcome measure scores completed between April 2016 and February 2024. Participants included individuals with an outcome collected before and after prosthesis receipt.<br />Results: The final sample size included 124 individuals (91 male, 33 female; 43.4 ± 15.0 years old, 34.4 ± 103.0 months since amputation, and 62.9% injury etiology). Analyses found significant improvement across all patients in the PROMIS-9 UE scores from baseline to post prosthesis intervention (baseline: 25.3 ± 8.6, post: 29.5 ± 9.6; p < 0.001). The PROMIS-9 UE demonstrated a moderate responsiveness (Standardized Response Mean = 0.6) to prosthetic intervention. This was a directional change consistent with subjective patient reports of increased functionality. Furthermore, findings from the linear mixed model demonstrated significant responsiveness for the PROMIS-9 UE instrument to detect post-intervention changes after controlling for potential confounding effects (p < 0.001).<br />Conclusions: These findings suggest the PROMIS-9 UE Physical Function instrument demonstrates moderate clinical utility in capturing patient progress following upper limb prosthesis intervention.<br />Competing Interests: Declarations. Ethics approval and consent to participate: Ethics approval for this retrospective study was obtained from the IRB Western Copernicus Group Institutional Review Board (protocol number 20170059). The study adhered to the ethical standards outlined in the Declaration of Helsinki. Consent for publication: Not applicable. Conflict of interest: The authors declare no conflict of interest with this work. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.<br /> (© 2025. The Author(s).)

Details

Language :
English
ISSN :
2509-8020
Volume :
9
Issue :
1
Database :
MEDLINE
Journal :
Journal of patient-reported outcomes
Publication Type :
Academic Journal
Accession number :
39928201
Full Text :
https://doi.org/10.1186/s41687-025-00843-y