Back to Search Start Over

In vitro gastrointestinal digestion of phlorotannins from Ulva lactuca: Nutritional value and implications in disease mechanisms through pharmacology network.

Authors :
López-Cárdenas FG
Mateos R
Sánchez-Burgos JA
Zamora-Gasga VM
Blancas-Benítez FJ
González-Cordova AF
Sáyago-Ayerdi SG
Source :
Food research international (Ottawa, Ont.) [Food Res Int] 2025 Mar; Vol. 204, pp. 115928. Date of Electronic Publication: 2025 Feb 04.
Publication Year :
2025

Abstract

Ulva lactuca, a green marine macroalga, is known for its potential health benefits due to bioactive compounds such as phlorotannins (PhT). This study aimed to identify and characterize the PhT profile in Ulva lactuca, evaluate their bioaccessibility, and explore their potential therapeutic targets through pharmacological network analysis. The study identified twenty PhT, showing a bioaccessibility of 54 %. Pharmacological network analysis revealed 54 potential targets associated with various disease pathways, including cancer. The findings highlight the nutritional value of Ulva lactuca and suggest the therapeutic potential of its PhT, offering new insights for future research and health applications.<br />Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2025. Published by Elsevier Ltd.)

Details

Language :
English
ISSN :
1873-7145
Volume :
204
Database :
MEDLINE
Journal :
Food research international (Ottawa, Ont.)
Publication Type :
Academic Journal
Accession number :
39986775
Full Text :
https://doi.org/10.1016/j.foodres.2025.115928