The role of microfilaments in the healing of the corneal endothelium.

Actin microfilaments are presumed to play a role in cell locomotion. The function of these filaments may be selectively suppressed by cytochalasin. A dose-dependent delay of the repair of a corneal endothelial defect by the application of cytochalasin in tissue culture has been observed by SEM. This observation confirms that the actin microfilaments are important for the endothelial repair.